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class=\"ul2_1\">\n<li>\n<p><div id=\"attachment_7929\" style=\"width: 395px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-7929\" src=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka1.png\" alt=\"\u52d5\u8108\u7624\u585e\u6813\u7528\u306e\u30b3\u30a4\u30eb\uff08\u30d7\u30e9\u30c1\u30ca\u88fd\uff09\" width=\"385\" height=\"312\" class=\"wp-image-7929 size-full\" srcset=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka1.png 385w, https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka1-300x243.png 300w\" sizes=\"auto, (max-width: 385px) 100vw, 385px\" \/><p id=\"caption-attachment-7929\" class=\"wp-caption-text\">\u52d5\u8108\u7624\u585e\u6813\u7528\u306e\u30b3\u30a4\u30eb\uff08\u30d7\u30e9\u30c1\u30ca\u88fd\uff09<\/p><\/div><\/li>\n<li>\n<p><div id=\"attachment_7930\" style=\"width: 386px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-7930\" src=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka2.jpg\" alt=\"\u52d5\u8108\u7624\u306b\u30b3\u30a4\u30eb\u3092\u5145\u586b\u3057\u305f\u69d8\u5b50\" width=\"376\" height=\"375\" class=\"wp-image-7930 size-full\" srcset=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka2.jpg 376w, https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka2-150x150.jpg 150w, https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka2-300x300.jpg 300w\" sizes=\"auto, (max-width: 376px) 100vw, 376px\" \/><p id=\"caption-attachment-7930\" class=\"wp-caption-text\">\u52d5\u8108\u7624\u306b\u30b3\u30a4\u30eb\u3092\u5145\u586b\u3057\u305f\u69d8\u5b50<\/p><\/div><\/li>\n<\/ul>\n<h4 class=\"mainTitle_2\">\u2461\u981a\u52d5\u8108\u30b9\u30c6\u30f3\u30c8\u7559\u7f6e\u8853<\/h4>\n<p>\u52a0\u9f62\u3068\u3068\u3082\u306b\u3001\u7279\u306b\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8102\u8840\u75c7\u306a\u3069\u306e\u57fa\u790e\u75be\u60a3\u304c\u3042\u308b\u65b9\u3067\u306f\u3001\u981a\u90e8\u304b\u3089\u8133\u3078\u7e4b\u304c\u308b\u5185\u981a\u52d5\u8108\u3068\u3044\u3046\u8840\u7ba1\u306b\u30d7\u30e9\u30fc\u30af\u3068\u3088\u3070\u308c\u308b\u8102\u304c\u4ed8\u7740\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u30d7\u30e9\u30fc\u30af\u306e\u4ed8\u7740\u91cf\u304c\u591a\u304f\u306a\u3063\u305f\u308a\u3001\u8106\u304f\u306a\u3063\u305f\u308a\u3059\u308b\u3068\u3001\u30d7\u30e9\u30fc\u30af\u304c\u4e00\u90e8\u5265\u304c\u308c\u3066\u3001\u305d\u3053\u306b\u8840\u6813\uff08\u8840\u306e\u584a\uff09\u304c\u3067\u304d\u307e\u3059\u3002\u305d\u308c\u304c\u8133\u3078\u98db\u6563\u3057\u3066\u3001\u8133\u306e\u8840\u7ba1\u3092\u8a70\u3081\u3066\u3057\u307e\u3044\u3001\u8133\u6897\u585e\u3092\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u30d7\u30e9\u30fc\u30af\u91cf\u304c\u975e\u5e38\u306b\u591a\u304f\u306a\u308b\u3068\u3001\u8133\u3078\u306e\u8840\u306e\u6d41\u308c\u3082\u60aa\u304f\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u305d\u306e\u3088\u3046\u306a\u5834\u5408\u306b\u3001\u30d7\u30e9\u30fc\u30af\u306e\u4ed8\u7740\u90e8\u306b\u30b9\u30c6\u30f3\u30c8\u3092\u7559\u7f6e\u3057\u3001\u30d7\u30e9\u30fc\u30af\u306b\u3044\u308f\u3070\u84cb\u3092\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u8133\u3078\u306e\u8840\u6d41\u3082\u6539\u5584\u3055\u305b\u3001\u8133\u6897\u585e\u3092\u4e88\u9632\u3057\u307e\u3059\u3002\u5f93\u6765\u884c\u308f\u308c\u3066\u304d\u305f\u5168\u8eab\u9ebb\u9154\u4e0b\u306b\u8840\u7ba1\u3092\u5207\u958b\u3057\u3001\u30d7\u30e9\u30fc\u30af\u3092\u53d6\u308a\u9664\u304f\u5185\u819c\u5265\u96e2\u8853\u3068\u6bd4\u8f03\u3057\u3066\u3082\u3001\u8133\u6897\u585e\u306e\u4e88\u9632\u52b9\u679c\u306f\u540c\u7b49\u3068\u3044\u3046\u30c7\u30fc\u30bf\u304c\u3067\u3066\u3044\u307e\u3059<span>(2010<\/span>\u5e74\u306e<span>CREST trial<\/span>\u3001<span>2016<\/span>\u5e74\u306e<span>ACT-1 trial<\/span>\u306e\u30c7\u30fc\u30bf\u3088\u308a<span>)<\/span>\u3002\u981a\u52d5\u8108\u30b9\u30c6\u30f3\u30c8\u7559\u7f6e\u8853\u306f\u5c40\u6240\u9ebb\u9154\u3067\u884c\u3048\u3001\u307e\u305f\u50b7\u3082\u30ab\u30c6\u30fc\u30c6\u30eb\u306e\u523a\u5165\u90e8\u3060\u3051\u306a\u306e\u3067\u3001\u8853\u5f8c\u56de\u5fa9\u304c\u65e9\u3044\u306e\u304c\u5229\u70b9\u3067\u3059\u3002<\/p>\n<ul class=\"ul2_1\">\n<li>\n<p><div id=\"attachment_7932\" style=\"width: 288px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-7932\" src=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka4.png\" alt=\"\u6cbb\u7642\u524d\" width=\"278\" height=\"442\" class=\"wp-image-7932 size-full\" srcset=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka4.png 278w, https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka4-189x300.png 189w\" sizes=\"auto, (max-width: 278px) 100vw, 278px\" \/><p id=\"caption-attachment-7932\" class=\"wp-caption-text\">\u6cbb\u7642\u524d<\/p><\/div><\/li>\n<li>\n<p><div id=\"attachment_7933\" style=\"width: 289px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-7933\" src=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka5.png\" alt=\"\u30b9\u30c6\u30f3\u30c8\u7559\u7f6e\u8853\u5f8c\" width=\"279\" height=\"440\" class=\"wp-image-7933 size-full\" srcset=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka5.png 279w, https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka5-190x300.png 190w\" sizes=\"auto, (max-width: 279px) 100vw, 279px\" \/><p id=\"caption-attachment-7933\" class=\"wp-caption-text\">\u30b9\u30c6\u30f3\u30c8\u7559\u7f6e\u8853\u5f8c<\/p><\/div><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4 class=\"mainTitle_2\">\u2782\u8133\u8840\u6813\u56de\u53ce\u8853<\/h4>\n<p>\u5fc3\u623f\u7d30\u52d5\u306a\u3069\u306e\u4e0d\u6574\u8108\u304c\u539f\u56e0\u3067\u3001\u5fc3\u81d3\u5185\u306b\u3067\u304d\u305f\u5927\u304d\u306a\u8840\u6813\u304c\u8133\u306e\u8840\u7ba1\u307e\u3067\u98db\u6563\u3057\u3001\u8a70\u307e\u3063\u3066\u3057\u307e\u3063\u305f\u8133\u6897\u585e\u306b\u5bfe\u3059\u308b\u7dca\u6025\u6cbb\u7642\u6cd5\u3067\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u30bf\u30a4\u30d7\u306e\u8133\u6897\u585e\u306f\u3001\u4e00\u65e6\u8d77\u3053\u308b\u3068\u5e83\u7bc4\u56f2\u306e\u8133\u3078\u306e\u8840\u6d41\u304c\u6b62\u307e\u3063\u3066\u3057\u307e\u3044\u3001\u8133\u304c\u58ca\u6b7b\u3057\u3066\u3001\u534a\u8eab\u9ebb\u75fa\u3084\u5931\u8a9e\uff08\u8a00\u8449\u304c\u8a71\u305b\u306a\u3044\uff09\u3001\u610f\u8b58\u969c\u5bb3\u306a\u3069\u91cd\u5ea6\u306e\u5f8c\u907a\u75c7\u3092\u6b8b\u3057\u3001\u5bdd\u305f\u304d\u308a\u3084\u6700\u60aa\u751f\u547d\u306b\u95a2\u308f\u308b\u3088\u3046\u306a\u4e8b\u614b\u3068\u306a\u308a\u307e\u3059\u3002\u4ee5\u524d\u306f\u5927\u304d\u306a\u8133\u8840\u7ba1\u304c\u8a70\u307e\u3063\u3066\u3057\u307e\u3046\u3088\u3046\u306a\u5e83\u7bc4\u56f2\u8133\u6897\u585e\u306b\u306f\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u304c\u3001\u306a\u304b\u306a\u304b\u306a\u304b\u3063\u305f\u306e\u3067\u3059\u304c\u30012015\u5e74\u306b\u306a\u3063\u3066\u30ab\u30c6\u30fc\u30c6\u30eb\u3092\u9589\u585e\u3057\u305f\u8133\u8840\u7ba1\u307e\u3067\u9032\u3081\u305f\u4e0a\u3067\u3001\u30b9\u30c6\u30f3\u30c8\u30ea\u30c8\u30ea\u30fc\u30d0\u30fc\u3068\u3044\u3046\u91d1\u5c5e\u306e\u6295\u7db2\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u3001\u8a70\u307e\u3063\u305f\u8840\u6813\u3092\u63bb\u304d\u51fa\u3059\u6cbb\u7642\u6cd5\u304c\u78ba\u7acb\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n\u305d\u308c\u307e\u3067\u306f\u8840\u6813\u6eb6\u89e3\u85ac\u3092\u70b9\u6ef4\u3057\u3066\u3082\u3001\u65e5\u5e38\u751f\u6d3b\u3092\u9001\u308c\u308b\u307e\u3067\u306b\u56de\u5fa9\u3067\u304d\u308b\u4eba\u306e\u5272\u5408\u304c30%\u306b\u3082\u6e80\u305f\u306a\u304b\u3063\u305f\u306e\u304c\u3001\u8840\u6813\u56de\u53ce\u8853\u3092\u884c\u3046\u3053\u3068\u306746%\u307e\u3067\u6539\u5584\u3067\u304d\u305f\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff082016\u5e74\u306eHERMES trial\u306e\u30c7\u30fc\u30bf\u3088\u308a\uff09\u3002\u305d\u306e\u305f\u3081\u73fe\u72b6\u3001\u65e5\u672c\u306e\u8133\u5352\u4e2d\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u9069\u5fdc\u306e\u3042\u308b\u60a3\u8005\u3055\u3093\u306b\u306f\u5fc5\u305a\u884c\u3046\u3079\u304d\u6cbb\u7642(\u63a8\u5968\u30b0\u30ec\u30fc\u30c9\uff1aA)\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6cbb\u7642\u306f\u60a3\u8005\u3055\u3093\u306e\u72b6\u614b\u306b\u3088\u3063\u3066\u306f\u8133\u6897\u585e\u767a\u75c724\u6642\u9593\u4ee5\u5185\u307e\u3067\u9069\u5fdc\u304c\u5e83\u304c\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u8133\u6897\u585e\u304c\u767a\u75c7\u3057\u3066\u6642\u9593\u304c\u65e9\u3051\u308c\u3070\u65e9\u3044\u307b\u3069\u52b9\u679c\u7684\u3067\u3059\u3002\u4e0a\u8a18\u306e\u3088\u3046\u306a\u9ebb\u75fa\u3084\u3057\u3083\u3079\u308a\u306b\u304f\u3055\u3001\u610f\u8b58\u304c\u304a\u304b\u3057\u3044\u306a\u3069\u3068\u3044\u3063\u305f\u75c7\u72b6\u304c\u51fa\u73fe\u3057\u305f\u5834\u5408\u306f\u3001\u305f\u3081\u3089\u308f\u305a\u6551\u6025\u8eca\u3092\u8981\u8acb\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u5f53\u9662\u3067\u306f24\u6642\u9593\u3001365\u65e5\u5c02\u9580\u533b\u304c\u6cbb\u7642\u306b\u5bfe\u5fdc\u3057\u3066\u304a\u308a\u307e\u3059\u3002\u307e\u305f\u65e5\u5e38\u751f\u6d3b\u5fa9\u5e30\u306b\u5411\u3051\u3066\u3001\u56de\u5fa9\u671f\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u75c5\u5e8a\u3092\u6301\u3064\u5f53\u9662\u7cfb\u5217\u306e\u516d\u7532\u30a2\u30a4\u30e9\u30f3\u30c9\u7532\u5357\u75c5\u9662\u3067\u8853\u5f8c\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u3092\u30b7\u30fc\u30e0\u30ec\u30b9\u306b\u884c\u3048\u308b\u4f53\u5236\u3092\u6574\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<ul class=\"ul2_1\">\n<li>\n<p><div id=\"attachment_7934\" style=\"width: 640px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-7934\" src=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka6.png\" alt=\"\u8840\u6813\u56de\u53ce\u7528\u306e\u30b9\u30c6\u30f3\u30c8\u30ea\u30c8\u30ea\u30fc\u30d0\u30fc\" width=\"630\" height=\"354\" class=\"wp-image-7934 size-full\" srcset=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka6.png 630w, https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka6-300x169.png 300w\" sizes=\"auto, (max-width: 630px) 100vw, 630px\" \/><p id=\"caption-attachment-7934\" class=\"wp-caption-text\">\u8840\u6813\u56de\u53ce\u7528\u306e\u30b9\u30c6\u30f3\u30c8\u30ea\u30c8\u30ea\u30fc\u30d0\u30fc<\/p><\/div><\/li>\n<li>\n<p><div id=\"attachment_7935\" style=\"width: 621px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-7935\" src=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka7.png\" alt=\"\u8840\u6813\u3092\u88dc\u8db3\u3059\u308b\u69d8\u5b50\" width=\"611\" height=\"389\" class=\"wp-image-7935 size-full\" srcset=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka7.png 611w, https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka7-300x191.png 300w\" sizes=\"auto, (max-width: 611px) 100vw, 611px\" \/><p id=\"caption-attachment-7935\" class=\"wp-caption-text\">\u8840\u6813\u3092\u88dc\u8db3\u3059\u308b\u69d8\u5b50<\/p><\/div><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul class=\"ul2_1\">\n<li>\n<p><div id=\"attachment_7936\" style=\"width: 289px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-7936\" src=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka8.png\" alt=\"\u53f3\u4e2d\u5927\u8133\u52d5\u8108\u9589\u585e\" width=\"279\" height=\"317\" class=\"wp-image-7936 size-full\" srcset=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka8.png 279w, https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka8-264x300.png 264w\" sizes=\"auto, (max-width: 279px) 100vw, 279px\" \/><p id=\"caption-attachment-7936\" class=\"wp-caption-text\">\u53f3\u4e2d\u5927\u8133\u52d5\u8108\u9589\u585e<\/p><\/div><\/li>\n<li>\n<p><div id=\"attachment_7937\" style=\"width: 138px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-7937\" src=\"https:\/\/kohnan.or.jp\/kohnan\/wp-content\/uploads\/2022\/07\/20220728_365_nougeka9.png\" alt=\"\u8840\u6813\u56de\u53ce\u3092\u884c\u3044\u3001\u518d\u958b\u901a\u3092\u8a8d\u3081\u307e\u3059\" width=\"128\" 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